Background: Heart rate variability (HRV) is an significant index of cardiovascular health and emotion regulation capacity. Cluster B Personality Disorder, Indicatetd the lowest emotion regulation capacity amongst others (Wilberg, 2009). Aims: The purpose of this study was to investigate the effect of excitement induced on all HRV frequncy domains. Although, Personality disorders was considered as moderating variables. Method: The target population of this research consisted of Iranian women and men aged 20 to 40 years whom referred to Binesh psychological clinic. 62 participants were selected through targeted sampling. This was an semi-experimental study. For analysing, mutivariable analyse of covariance, repeatitive measurement with P<0.05 was selected. The research tools included Procomp HRVBiofeedback (2012), excitement emerging movies (Schaefer, 2010), and SWAP-200 Interview (2007). Results: According to the findings, people with cluster B personality disorders showed the most changes in HRV ferquency domains,then cluster B and C in turns, revealed changes (P<0.05 for all groups). According to the results, the worst emotion regulation in cluster B has significant relationship with the worst HRV. Conclusions: Therefore, Emotion regulation as a Psychological factor can be impressive in Cardiovascular Health.