Background: Numerous studies have examined defensive styles, emotional failure, and maladaptive schemas, and the relationship between these variables, but a study that compares defensive styles, emotional disharmony, and maladaptive schemas in people with asthma and normal people is neglected. remained. Aims: To compare defensive styles, emotional inadequacies, and maladaptive schemas in people with asthma and normal individuals. Method: The present study was causal-comparative. The statistical population of the present study was all people with asthma who had referred to Razi and occupational medicine clinics in Yazd in the spring and summer of 1398, as well as people working in clinics and family members of people with asthma. 100 people with asthma and 100 normal people aged 38 to 62 years were selected as available and targeted sampling. Research tools include the Andros et al. (1993) Defensive Styles Questionnaire, the Toronto Emotional Disappointment Scale (1994), and the Young Project Schedule (1998). Data analysis was performed using multivariate analysis of variance. Results: There is a significant difference between people with asthma and normal people in undeveloped defensive style, emotional failure and maladaptive schema (p< 0/01). Conclusions: Untreated defensive style, emotional distress and maladaptive schemas increase the risk of developing asthma.