Sahar Maleki Sad Abadi, Javid Peymani, Mansooreh Tajvidi, Saied Malihialzackerini, Mahdi Shahnazari,
Volume 25, Issue 160 (6-2026)
Background: Neurodegenerative disease is caused by the progressive loss of neurons in a process called neurodegeneration. This group of diseases is accompanied by a gradual loss of sensory-motor, cognitive, perceptual, and behavioral abilities.
Aims: The purpose of the present study was the meta-analysis of the research conducted on the effectiveness of psychological interventions on the quality of life of patients with neurodegenerative diseases in Iran.
Methods: The method of this research was meta-analysis. From the set of research conducted in the field of the effectiveness of psychological interventions on the quality of life of patients with neurodegenerative diseases in Iran between 2015-2024, the studies that were acceptable in terms of methodology and met the criteria for entering this meta-analysis, 11 studies were selected by purposive sample. The total sample size of this research was 314 people. CMA-2 software was used to conduct the meta-analysis. A forest plot, funnel plot, and publication bias table were drawn using this software.
Results: The results showed that psychological interventions are effective in the quality of life of patients with neurodegenerative diseases. I2 and Q tests were used to analyze heterogeneity and the results showed significant heterogeneity (I2=92.792, P=0.001).
Conclusion: The result of the present study indicated that the effect size of psychological interventions on the quality of life of neurodegenerative patients in Iran is acceptable. This indicates the possible effect of increasing the knowledge and awareness of patients as well as the level of insight of the families of these patients regarding quality of life indicators in the country.