Enter your email address
Submit
Write your message
Volume 24, Issue 155 (12-2025)
Journal of Psychological Science 2025, 24(155): 13-22 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Heshmati R, Kishi E, louise caltabiano M. (2025). Neuropsychological profile of memory and attention in individuals with temporal lobe epilepsy and its comparison with healthy people. Journal of Psychological Science. 24(155), 13-22. doi:10.61186/jps.24.155.2
URL: http://psychologicalscience.ir/article-1-3112-en.html
URL: http://psychologicalscience.ir/article-1-3112-en.html
Department of Psychology, Faculty of Educational Sciences and Psychology, University of Tabriz, Tabriz, & Department of Psychology, Faculty of Educational Sciences and Psychology, University of Tabriz, Tabriz, Iran. , elhamkishi1@gmail.com
Abstract: (2605 Views)
Background: Epilepsy is associated with multiple neuropsychological deficits, and various studies have reported impairments in memory, language, executive functions, and attention. This condition can significantly affect social interactions and communication, leading to challenges in daily life.
Aims: The present study aimed to investigate the neuropsychological profile of attention and associative memory in individuals with temporal lobe epilepsy (TLE) and compare it with healthy individuals.
Methods: The research employed a descriptive, causal-comparative design. Sixty individuals with temporal lobe epilepsy and 60 healthy individuals (N= 120) comprised the sample. The Wechsler Memory Scale(Wechsler, 1945) for Adults and the Integrated Visual and Auditory Continuous Performance Test(Berginström et al., 2015) were used to measure variables. Data analysis was conducted using an independent t-test and its non-parametric equivalent, the Mann-Whitney U test.
Results: The results indicated a significant difference in associative memory between individuals with epilepsy and healthy individuals (Z= 8.90, p< 0.01). Moreover, a significant difference was found in auditory attention between the two groups (Z= 8.18, p< 0.01). Finally, there was a significant difference in visual attention between individuals with epilepsy and healthy individuals (Z= 9.90, p< 0.01).
Conclusion: The study’s findings suggest that individuals with temporal lobe epilepsy exhibit significant deficits in memory and attention compared to their healthy counterparts. These findings highlight the importance of the temporal lobe in cognitive processes and emphasize the necessity of neuropsychological assessments in treatment programs to improve the quality of life for these patients.
Aims: The present study aimed to investigate the neuropsychological profile of attention and associative memory in individuals with temporal lobe epilepsy (TLE) and compare it with healthy individuals.
Methods: The research employed a descriptive, causal-comparative design. Sixty individuals with temporal lobe epilepsy and 60 healthy individuals (N= 120) comprised the sample. The Wechsler Memory Scale(Wechsler, 1945) for Adults and the Integrated Visual and Auditory Continuous Performance Test(Berginström et al., 2015) were used to measure variables. Data analysis was conducted using an independent t-test and its non-parametric equivalent, the Mann-Whitney U test.
Results: The results indicated a significant difference in associative memory between individuals with epilepsy and healthy individuals (Z= 8.90, p< 0.01). Moreover, a significant difference was found in auditory attention between the two groups (Z= 8.18, p< 0.01). Finally, there was a significant difference in visual attention between individuals with epilepsy and healthy individuals (Z= 9.90, p< 0.01).
Conclusion: The study’s findings suggest that individuals with temporal lobe epilepsy exhibit significant deficits in memory and attention compared to their healthy counterparts. These findings highlight the importance of the temporal lobe in cognitive processes and emphasize the necessity of neuropsychological assessments in treatment programs to improve the quality of life for these patients.
Type of Study: Research |
Subject:
Special
Received: 2025/07/13 | Accepted: 2025/09/16 | Published: 2025/12/26
Received: 2025/07/13 | Accepted: 2025/09/16 | Published: 2025/12/26
References
1. Aydemir, N., Özkara, Ç., Ünsal, P., & Canbeyli, R. (2011). A comparative study of health related quality of life, psychological well-being, impact of illness and stigma in epilepsy and migraine. Seizure, 20(9), 679-685. https://doi.org/10.1016/j.seizure.2011.06.017
2. Azizi, M., & Afrooz, G. A. (2025). Comparison of lifestyle and spiritual vitality among elderly people over 80 with Alzheimer's disease and those without Alzheimer's disease [Research]. Journal of Psychological Science, 24(146), 11-25. http://psychologicalscience.ir/article-1-2675-en.html
3. Berginström, N., Johansson, J., Nordström, P., & Nordström, A. (2015). Attention in older adults: a normative study of the integrated visual and auditory continuous performance test for persons aged 70 years. The Clinical Neuropsychologist, 29(5), 595-610. https://doi.org/10.1080/13854046.2015.1063695
4. Cairós-González, M., Verche, E., Hernández, S., & Alonso, M. Á. (2024). Cognitive flexibility impairment in temporal lobe epilepsy: The impact of epileptic foci lateralization on executive functions. Epilepsy & Behavior, 151, 109587. https://doi.org/10.1016/j.yebeh.2023.109587
5. Cano-López, I., Catalán-Aguilar, J., Lozano-García, A., Hidalgo, V., Hampel, K. G., Tormos-Pons, P.,... González-Bono, E. (2024). Cognitive phenotypes in patients with drug-resistant temporal lobe epilepsy: Relationships with cortisol and affectivity. The Clinical Neuropsychologist, 1-24. https://doi.org/10.1080/13854046.2024.2375605
6. Condret-Santi, V., Barragan-Jason, G., Valton, L., Denuelle, M., Curot, J., Nespoulous, J.-L., & Barbeau, E. J. (2014). Object and proper name retrieval in temporal lobe epilepsy: A study of difficulties and latencies. Epilepsy research, 108(10), 1825-1838. https://doi.org/10.1016/j.eplepsyres.2014.09.001
7. Eskandari, M., Zarghami, M., Azizi, M., & Eskandari, E. (2024). Comparison of cognitive performance before and after the presentation of different levels of noise in the employees of light vessels operating in the Persian Gulf [Original Article]. Journal of Marine Medicine, 6(1), 72-79. https://doi.org/10.30491/6.1.72
8. Falah, A., & Winston, G. P. (2024). Comparative analysis of processing speed impairments in TLE, FLE, and GGE: Theoretical insights and clinical Implications. Epilepsy & Behavior Reports, 100722. https://doi.org/10.1016/j.ebr.2024.100722
9. Fleury, M., Buck, S., Binding, L. P., Caciagli, L., Vos, S. B., Winston, G. P., Sidhu, M. K. (2022). Episodic memory network connectivity in temporal lobe epilepsy. Epilepsia, 63(10), 2597-2622. https://doi.org/10.1111/epi.17370
10. Hartmann, S. (2002). A self‐adapting genetic algorithm for project scheduling under resource constraints. Naval Research Logistics (NRL), 49(5), 433-448. https://doi.org/10.1002/nav.10029
11. Helmstaedter, C., Tailby, C., & Witt, J. (2024). Neuropsychology of late-onset epilepsies. Seizure: European Journal of Epilepsy. https://doi.org/10.1016/j.seizure.2024.06.022
12. Hoxhaj, P., Habiya, S. K., Sayabugari, R., Balaji, R., Xavier, R., Ahmad, A.,... Abdin, Z. U. (2023). Investigating the Impact of Epilepsy on Cognitive Function: A Narrative Review. Cureus, 15(6). https://assets.cureus.com/uploads/review_article/pdf/159979/20230730-22668-1t3ge7i.pdf
13. karimi Lichahi, R., Akbari, B., Hoseinkhanzadeh, A. A., & asadi majreh, s. (2021). The Effectiveness of Sensory-Motor Integration Trainingon working memory and visual-motor coordination ofDyslexic Students [Original Article]. Journal of Exceptional Education (J Except Educ), 1(161), 0. http://exceptionaleducation.ir/article-1-2368-en.html
14. Keary, T. A., Frazier, T. W., Busch, R. M., Kubu, C. S., & Iampietro, M. (2007). Multivariate neuropsychological prediction of seizure lateralization in temporal epilepsy surgical cases. Epilepsia, 48(8), 1438-1446. https://doi.org/10.1111/j.1528-1167.2007.01098.x
15. Kishi, E., & Azizi, M. (2025). Comparison of Cognitive Performance in Elderly Individuals With and Without a History of Music Training. Recent Innovations in Psychology, -. https://doi.org/10.22034/rip.2025.495572.1075
16. Kokkinos, V., & Seimenis, I. (2024). Concordance of verbal memory and language fMRI lateralization in people with epilepsy. Journal of Neuroimaging, 34(1), 95-107. https://doi.org/10.1111/jon.13171
17. Kwan, A. C., Olson, D. E., Preller, K. H., & Roth, B. L. (2022). The neural basis of psychedelic action. Nature Neuroscience, 25(11), 1407-1419. https://doi.org/10.1038/s41593-022-01177-4
18. Lin, J. J., Mula, M., & Hermann, B. P. (2012). Uncovering the neurobehavioural comorbidities of epilepsy over the lifespan. The Lancet, 380(9848), 1180-1192. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)61455-X/abstract
19. Menlove, L., & Reilly, C. (2015). Memory in children with epilepsy: a systematic review. Seizure, 25, 126-135. https://doi.org/10.1016/j.seizure.2014.10.002
20. Miller, L. A., Galioto, R., Tremont, G., Davis, J., Bryant, K., Roth, J., Blum, A. S. (2016). Cognitive impairment in older adults with epilepsy: characterization and risk factor analysis. Epilepsy & Behavior, 56, 113-117. https://doi.org/10.1016/j.yebeh.2016.01.011
21. Naeeniyan, M. R. (2004). Comparing some Cognitive Processes in Epileptic Patients before and after Treatment. Clinical Psychology and Personality, 2(2), 17-22. https://cpap.shahed.ac.ir/article_2573_7a921db4925faecfb0be3358884582c3.pdf
22. Reyes, A., Holden, H. M., Chang, Y.-H. A., Uttarwar, V. S., Sheppard, D. P., DeFord, N. E., McDonald, C. R. (2018). Impaired spatial pattern separation performance in temporal lobe epilepsy is associated with visuospatial memory deficits and hippocampal volume loss. Neuropsychologia, 111, 209-215. https://doi.org/10.1016/j.neuropsychologia.2018.02.009
23. Ryan, K. M. (1981). Developmental differences in reactions to the physically disabled. Human Development, 24(4), 240-256. https://doi.org/10.1159/000272685
24. Stafstrom, C. E., & Carmant, L. (2015). Seizures and epilepsy: an overview for neuroscientists. Cold Spring Harbor perspectives in medicine, 5(6), a022426.https://perspectivesinmedicine.cshlp.org/content/5/6/a022426.full.pdf
25. Sternberg, R. J. (2013). Wisdom, intelligence, creativity, synthesised: a model of giftedness. In The Routledge international companion to gifted education (pp. 255-264). Routledge.https://www.taylorfrancis.com/chapters/edit/10.4324/9780203609385-37/wisdom-intelligence-creativity-synthesised-model-giftedness-robert-sternberg
26. Suzuki, W. A. (2005). Psychological science agenda| february 2005. Psychological Science.
27. Tani, A., & Adali, N. (2024). Effective Factors in Cognitive Functions of Patients with Temporal Lobe Epilepsy. Archives of Neuroscience, 11(2).
28. Tedrus, G. M. A. S., Santos, L. M. d., & Meneghetti, F. (2021). Older adults with epilepsy: memory complaints and objective neuropsychological performance. Arquivos de Neuro-Psiquiatria, 79(2), 133-138. https://doi.org/10.1590/0004-282X-ANP-2020-0209
29. Thompson, K., Lo, A. H., McGlashan, H. L., Ownsworth, T., Haslam, C., Pegna, A., & Reutens, D. C. (2024). Measures of subjective memory for people with epilepsy: a systematic review of measurement properties. Neuropsychology Review, 34(1), 67-97. https://doi.org/10.1007/s11065-022-09568-x
30. Tuchscherer, V., Seidenberg, M., Pulsipher, D., Lancaster, M., Guidotti, L., & Hermann, B. (2010). Extrahippocampal integrity in temporal lobe epilepsy and cognition: thalamus and executive functioning. Epilepsy & Behavior, 17(4), 478-482. https://doi.org/10.1016/j.yebeh.2010.01.019
31. Walker, L. A., Lindsay-Brown, A. P., & Berard, J. A. (2019). Cognitive fatigability interventions in neurological conditions: a systematic review. Neurology and therapy, 8, 251-271. https://doi.org/10.1007/s40120-019-00158-3
32. Wang, K., Xie, F., Liu, C., Wang, G., Zhang, M., He, J.,... Wan, L. (2024). Chinese verbal fluency deficiency in temporal lobe epilepsy with and without hippocampal sclerosis: a multiscale study. Journal of Neuroscience, 44(37). https://doi.org/10.1523/JNEUROSCI.0558-24.2024
33. Weiping, X., & Lixiao, S. (2015). Comorbid anxiety and depression in school-aged children with attention deficit hyperactivity disorder (ADHD) and selfreported symptoms of ADHD, anxiety, and depression among parents of school-aged children with and without ADHD. Shanghai archives of psychiatry, 27(6), 356. https://doi.org/10.11919/j.issn.1002-0829.215115
34. Wills, K. E., González, H. F., Johnson, G. W., Haas, K. F., Morgan, V. L., Narasimhan, S., & Englot, D. J. (2021). People with mesial temporal lobe epilepsy have altered thalamo-occipital brain networks. Epilepsy & Behavior, 115, 107645. https://doi.org/10.1016/j.yebeh.2020.107645
35. Yang, H., Wei, X., Huang, K., Wu, Z., Zhang, Q., Wen, S.,... Feng, L. (2024). Features of attention network impairment in patients with temporal lobe epilepsy: Evidence from eye-tracking and electroencephalogram. Epilepsy & Behavior, 157, 109887. https://doi.org/10.1016/j.yebeh.2024.109887
36. Yazdanbakhsh, K., & Azarnia, A. (2023). The Effectiveness of Cognitive Rehabilitation on Improving the Cognitive Abilities of the Elderly. Iranian Journal of Ageing, 18(1), 32-45. http://dx.doi.org/10.32598/sija.2022.3258.1
37. Zhao, F., Kang, H., You, L., Rastogi, P., Venkatesh, D., & Chandra, M. (2014). Neuropsychological deficits in temporal lobe epilepsy: A comprehensive review. Annals of Indian Academy of Neurology, 17(4), 374-382. https://journals.lww.com/annalsofian/fulltext/2014/17040/Neuropsychological_deficits_in_temporal_lobe.3.aspx
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) License. |
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)