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Volume 24, Issue 146 (4-2025)                   Journal of Psychological Science 2025, 24(146): 239-253 | Back to browse issues page

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Jalali rigi M, Ansari Shahidi M, Heyrani Tabas A. (2025). Investigating the Effect of Cell Therapy on increasing Serotonin Secretion in Depression By Stem Cells. Journal of Psychological Science. 24(146), 239-253.
URL: http://psychologicalscience.ir/article-1-2481-en.html
, ravanshenas310@gmail.com
Abstract:   (491 Views)
Background and purpose: Stem cells play an important role in tissue regeneration and disease treatment, so the present study was conducted with the aim of investigating the effect of cell therapy on increasing serotonin secretion in depression by cells.
Method: This research was practical in terms of its purpose and in terms of experimental implementation with a pre-test and post-test design with a control group. The statistical population of the research was adult Syrian rats, known as Syrian rats. 40 Syrian rats were purposefully selected as samples based on the research entry criteria, and were randomly divided into two experimental and control groups (20 in each group). First, the blood serotonin levels of the two groups were measured. Then the test group received umbilical cord stem cells through injection and at this time the control group did not receive any intervention. After receiving the stem cells, the level of serotonin secretion in the two groups was re-examined, SPSS version 25 Software and un ivariate covariance analysis were used in the data analysis.
Findings: The results showed that by controlling the effect of the pre-test, there was a significant difference between the average post-test serotonin secretion in the experimental and control groups (p<0.01), so cell therapy increases the serotonin secretion in depression by cells. It has become fundamental.
Conclusion: Stem cells can be considered promising for the treatment of cognitive and mental diseases and new developing strategies for the treatment of nervous system diseases including depression.
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Type of Study: Research | Subject: Special
Received: 2024/05/31 | Accepted: 2024/08/5 | Published: 2025/02/3

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This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)